Preclinical Development of Targeted Stereotactic Body Radiation Therapy for Pancreatic Cancer
نویسندگان
چکیده
منابع مشابه
Stereotactic Body Radiation Therapy (SBRT) for Unresectable Pancreatic Carcinoma
Survival in patients with unresectable pancreatic carcinoma is poor. Studies by Mayo Clinic and the Gastrointestinal Tumor Study Group (GITSG) have established combined modality treatment with chemotherapy and radiation as the standard of care. Use of gemcitabine-based chemotherapy alone has also been shown to provide a benefit, but 5‑year overall survival still remains less than 5%. Convention...
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Introduction Pancreatic adenocarcinoma is an aggressive malignancy that has consistently demonstrated poor outcomes despite aggressive treatments. Despite multimodal treatment, local disease progression and local recurrence are common. Management of recurrent or progressive pancreatic carcinomas proves a further challenge. In patients previously treated with radiation therapy, stereotactic body...
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Song and colleagues deliver a thorough and fair review of the initial clinical investigations of a new paradigm in radiotherapy most recently called stereotactic body radiation therapy (SBRT).[1] Oncology observers may take exception with the use of the designation “new paradigm.” After all, from a tumor control point of view, skeptics might say, “radiotherapy is radiotherapy.” Recent advances ...
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ژورنال
عنوان ژورنال: International Journal of Radiation Oncology*Biology*Physics
سال: 2017
ISSN: 0360-3016
DOI: 10.1016/j.ijrobp.2017.06.2464